BEIJING -- Chinese scientists have made a breakthrough in creating stem cells with a cocktail of two chemicals that can induce mature somatic cells to turn back into pluripotent stem cells.The study by scientists from the Guangzhou Institutes of Biomedicine and Health, of the Chinese Academy of Sciences, will help understanding of the fate of cells and could be applied to regenerative medicine, said lead researcher Pei Duanqing.Scientists around the world are looking for "keys" that enable humans to regrow tissue or organs lost due to illness or injury, like a gecko can regrow a tail.Stem cells can self-renew or multiply while maintaining the potential to develop into other types of cells. They can become cells of the blood, heart, bones, skin, muscle, brain or other body parts. They are valuable research tools and might, in future, be used to treat a wide range of ailments.But how can we get enough stem cells?Scientists around the globe have tried different approaches to induce somatic cells into stem cells. Japanese Nobel Laureate Shinya Yamanaka utilized a virus as a carrier to generate induced stem cells, but this method is believed to have a high risk of causing cancer.Chinese scientists have spent five years developing a method of chemical induction, which is more efficient, simpler and safer."The fate of cells is determined by the chromatin structure in the nucleus of cells," said Liu Jing, a member of the research team. "We use small molecular chemicals to reprogram the somatic cells by manipulating the chromatin structure from the somatic cell pattern to stem cell pattern."Soaking various somatic cells in the chemicals can induce them to become pluripotent stem cells, including the hepatic cell, which is difficult to reprogram by other methods, Liu added.The study is published in the latest issue of Cell Stem Cell. wristbands canada
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China's unmanned submersible Hailong III enters the water for a deep water test on April 4, 2018. China's unmanned submersible Hailong III dived 4,266 meters below the sea surface in the western Pacific Ocean late Wednesday while conducting a 4,500-meter level deep water test. [Photo/Xinhua] DAYANG YIHAO - China's unmanned submersible Hailong III dived 4,266 meters below the sea surface in the western Pacific Ocean late Wednesday while conducting a 4,500-meter level deep water test. The submersible entered the water from its mothership Dayang Yihao (Ocean No. 1), a Chinese scientific research ship, at 6:30 pm Beijing time (1030 GMT). It reached the depth of 4,266 meters some 174 minutes later, and returned to the deck of the mothership early on Thursday. Yang Lei, head of a panel involved in Wednesday's sea test, said Hailong III has broad prospects in application in deep-sea exploration, and could be a favorable work platform for marine observation, deep-sea exploration and sampling. Chu Fengyou, chief scientist of Dayang Yihao, said the submersible, which is able to dive to a depth of 6,000 meters, has completed a 400-meter level shallow sea test on March 24 and a 2,000-meter level test on the following day. The submersible was scheduled to take the 4,500-meter level deep water test in late March, but Dayang Yihao could not find an ideal place for the submersible to carry out its tasks due to the influence of Typhoon Jelawat, said Chu. The area where the submersible dived a depth of 4,266 meters was the best location at the time, said Chu, adding that the neighboring sea areas could not meet the requirements for the submersible to complete the test. Dayang Yihao departed China's eastern port city of Qingdao on March 20, taking scientists on a 45-day scientific expedition. Hailong literally means Sea Dragon in Chinese.
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